Although I have never experienced Adverse effect during clinical trials, I agree to the possibly of incorporating wearable technologies into the protocol for effective physiological monitoring. AE’s are unanticipated and the wearable sensors provide supporting documentation which can be used…   Read more»

It is important to blind and randomize during clinical trials. Like others have stated, randomization helps to ensure that the different groups are all tested with a diverse population. This helps to test a treatment or device through a wider…   Read more»

I actually didn’t know this law existed! At a glance it sounds like a good thing. For terminally ill patients this could provide a sliver of hope or a chance for them to contribute to science. Given my limited knowledge…   Read more»

The original post mentions that “Placebo is better than no treatment” however I believe placebo means no treatment is actually given. For example a placebo for an injectable drug could be a saline injection.  I do see the ethical dilemmas…   Read more»

My opinion is that humans have a right to decide what they want to do with their body including whatever is removed during a surgery. Some people do not want their tissues/specimen to be part of research and  to me…   Read more»

Clinical studies are necessary for the advancement of medical technology and medication. Assuming the application of the product provides ideal results, the primary advantage of a clinical trial is simply the access to this particular treatment over other common treatments….   Read more»

In terms of advantages, clinical trials help to see if treatments are effective and are sometimes for novel treatment options. In terms of disadvantages, the treatment from the clinical trial could have adverse effects on the patients as the effect…   Read more»

@maniakberk I agree with @maniakberk. If the inclusion of a placebo does not harm the patient, I think it would be better to include placebos as well. They also mentioned how they believed a placebo-controlled trial could positively affect the…   Read more»

Posted by: @amandaally1029 With clinical studies comes lots of risks, especially where human participants are concerned. However, in order to figure out if a medical product, device, or drug is essential, these studies are necessary. What do you think are…   Read more»

Posted by: @merzkrashed As Dr.Simon mentioned about placebo-controlled trials, which is A “dummy” device or drug is used on one group of patients and compared to patients with the real one, or sometimes called a ‘sugar pill. Or a fake…   Read more»

Randomization and blinding are considered to be characters of best study design, but the “Gold Standard” Clinical trial are Randomized double blind placebo control. It eliminate the influence of  immeasurable variables that may lead to biased and incorrect estimate of…   Read more»

one thing to add is clinical trails for drugs takes at least 10 years to develop new medicine. It take a lot o time for development and getting FDA for approval. I have red and i am quoting “Less than…   Read more»

This is an interesting topic and it is also interesting to see that some people chose the Utilitarianism approach, where the “justified” scarifies of life is thought to be okay, as long as it served a higher purpose of benefiting…   Read more»

I would respectfully disagree that only medical devices have been proven to improve human health, and not pharmaceuticals. In addition, a drug does not need to cure a disease in order to be classified as effective or safe. Reducing side…   Read more»

This is indeed a sensitive topic since are dealing with the death of a person, however, before accusing someone, an investigation must take place to evaluate the root cause of death. Also, the question itself is very vague; are we…   Read more»

There are pros and cons for these types of studies. Like you mentioned, they are able to gather a lot more clinical evidence in a shorter time than a single trial and can encompass a larger number of patients that…   Read more»

Posted by: @sam-doksh Clinical research is a is the study of health , it is important for the progress of modern medicine. It determine the safety and efficacy of medications, devices, and treatment regimens intended for human use.    …   Read more»

I believe placebo-controlled trials are necessary and can be done ethically, since previous studies have shown the placebo-effect to be apparent in a wide range of fields. The mechanism behind the placebo-effect is still not quite fully understood, but multiple…   Read more»

I think having a clinical background is not necessary, since people can learn while interacting with the patients on the spot, however, there are many benefits to having a clinical background. Since having a clinical background is a plus, it…   Read more»

I believe it is acceptable to expose a few human subjects to risk of harm for the benefit of future patients, since those few human subjects are told of all the risks and benefits of the clinical trial and make…   Read more»