I think it’s better to outsource if you aren’t as qualified to run a clinical trial. If you lack the resources in man power and knowledge you are better off hiring a CRO to do the clinical trial for you. This could prevent many pitfalls that can result in added costs to the clinical trial which is already very expensive. If the company has the man power and the monetary resources to run this clinical trial then it’s okay to do it in house. It also depends on what is most favorable with the FDA. If they are looking for particularly certifications or procedures followed then the CRO might be more qualified to run the trial and increase chances of the FDA approving of the while process.