ec52 and Sk90, thank you for your responses. The answers you’ve provided about CRO selection criteria, questions to ask when inquiring about them, and selecting at least three to evaluate are valuable insights. Sk90, the data exporting point you bring up is becoming more and more important as technology evolves, will the data be stored onsite or will they be using the cloud? the security concerns about these storage options are valid. Cost, transparency and responsiveness play into the idea that a larger CRO may be less responsive to a small trial due to the fact that they aren’t bringing in as much revenue as larger trials. ec52, selecting team members with the correct experience and background as the individuals to evaluate the CROs is also another valid point.