Hi Fady and Luisa,

I would agree that it is a difficult measurement to simply say that every time a certain number. However I would agree with Luisa that a study needs to be clearly defined and there needs to be enough patients in each center. I believe that one of the most important things is ensuring that there is enough patients at each center to ensure accurate data. As Luisa said, this line would be drawn when a a center when you have enough people at the center and enough staffers to correctly run the study.

-Andrew Nashed