I don’t believe there is really an expiration date for a validation. Each installation qualification process gets updated every year or so. Due to this, it accounts for any changes that may occur in terms of technology, new specifications, and new parameters. Also, if there is a deficiency that occurs with the product this would certainly create a need to update the validation procedures and revalidate the process. So, to your point I don’t believe a validation has an expiration date because there are always going to be updates and changes occurring.