Your last two words meeting expectations raised another very important question. What if the CROs do not meet the expectations or deliver the expected result?

And I agree with your choice of responsibilities that will be better if handled by the sponsor himself. Monitors and investigators are the key components in the clinical trial. If you do not know the monitors/investigators of the task you transferred over, then you as a sponsor won’t be satisfied with the results. If you personally know who is working on your task and their ability to think outside the box. Then you will be more likely to get the results you expected.

Again, what do you guys think happens if a CRO is unable to deliver the expected results? Has this ever happened from your experience or to your knowledge?