Many times the clinical trials conducted by the CRO are done with the intention of gaining maximum profit out of the business without any concern for the safety and efficacy of the patients. In my opinion, the outsourcing policy only benefits the organization by extracting the poor, illiterate and needed population by giving them lucrative offers. In the past there have been some cases of unethical outsourcing done in India and Nigeria. In one of the case, the unethical clinical trials was conducted on the Bhopal gas tragedy victims, without informing them and without asking their consents.Thus, I feel it must be minimized in the developing nations. And the deign regulations must make sure that there is no compromise with the human safety. If the company decides to outsource ,the job opportunities should not be curtailed and the human volunteers should be treated with respect and they should be properly informed and their consent must be taken.