Project manager is both jobs has its own rules and regulations. For example, in medical devices the person has to make sure that the product is safe and able to pass all the FDA regulations. While in construction, they have to make sure that buildings are safe in general as well as during earthquake, fire hazard etc. This also depends on where the construction is held. In cities like lisbon, earthquake is most important. While in california fire hazard etc. So in short, there are challenges in both jobs, the only difference is that they are bit different from each other.