Like many have mentioned- I believe the main difference of being a project manager for a medical device company is that it is a highly regulated field and different countries have different regulations. Some have mentioned the novelty and uncertainty when it comes to devices and FDA regulations, but if there is a similar existing medical device on the market with FDA approval, then its easier to plan just as if there was a similar already existing skyscraper that passed regulations. If it is a novel device then there needs to be more work upfront, and even considering aspects like IP. If filed on the medical device you want to make sure you are focused and can obtain regulatory approval so you have enough time to bring the device to market and actually make money before the patent expires.

As Bhargav mentioned, there will always be regulations and challenges to consider and Project Managers will encounter similar challenges across industries.