As the others stated above, its essential to follow the ISO 10993 table in regards to implants, or orthopedics. However, when it comes to neural biomaterials, or drugs used to aid in other areas of the body, you should also consider performing an ADME test. This will allow us to see whether the drugs have acceptable absorption, distribution, metabolism, and excretion. Its important to make sure that drugs can travel to its targeted place successfully and reacts the way its expected.