Every Coin has two sides of it in the same way every clinical trials has advantages and disadvantages:-

Advantages :-
1. You may gain access during and after the clinical trial to new treatments that are not yet available to the general population
2. You may obtain medical care free of charge
3. You will be closely monitored for possible adverse events
4. You are contributing to medical research that may result in the advancement of medicine and healthcare in general thereby helping other fellow human beings
5. Participating in clinical trials is not a source of primary or additional income. However almost all sponsors reimburse persons that participate in trials for all reasonable expenses related to participating in the trial, including travel expenses, food, medical care and compensation for provable and insured adverse events that are related to the trial.

Disadvantages:-
1. You may need to set aside time for trial related activities like visiting the trial site
2. You may not use certain medications including traditional medications without the approval of your trial doctor
3. Your personal private or social life may be affected, e.g. sexual activity, reproductive functioning, consumption of alcohol, tobacco or other drugs of abuse, etc.
4. You may have to consult your usual healthcare provider for all your other illnesses that are not related to the trial, but still you have to inform your provider that you are part of a trial and that certain medications or treatment options may not be compatible with your trial protocol
5. Your employer, medical aid, personal insurance and/or Commissioner for Compensation for Occupational Injuries may not pay for claims that are related to events due to your participation in clinical trials; it is therefore extremely important that you verify that the sponsor of the trial has an appropriate comprehensive insurance cover for you.