I believe that clinical studies are necessary in order to determine the best possible treatment for a disease or other pathology. There are some advantages to the participant as well, being monetary compensation and follow up check-ups for a potential treatment that may help their disease. It may also be an advantage to some since they are contributing to medical research that can become a medical advancement for the rest of the population. The participant may also obtain medical care free of charge. Some of the disadvantages include that the participant may have serious adverse events that are related to the treatment and their lives may be ruined if something does go wrong. In the long run, it seems like an individual decision to make to be a “human guinea-pig.”