I agree with the points the above students have stated. Clinical trials are done because doctors are trying to improve science and medication. There are many ways to test if a medication or a procedure will work but in certain cases, the only way to know if it works is through clinical trials. Doctors will have myriads of research about the procedure and know what they are doing. So with that trust and the trust that they will inform us about all the risks and complications of the procedure, we can decide ourselves if we would like to participate in the trial.
Although some trials might not be approved, when presented with all the information, I don’t think clinical trials are unethical. Trials might have a very low chance of survival like 1% as Ibraheem has stated but it is a 1% chance of surviving and being cured from a cancer or disease. When all the information is shared with the patient, there should be no ethical issues involved.