Clinical trials are risky, but I do not agree to inhibit doing clinical trials, since it is very important for research. In my opinion, a strategy should be required for reducing the risk comes from clinical trials.
For example, participants may do some blood test before clinical trials to make sure they are really suitable for joining the test. Or participants can take very small dose drug first, then do blood test to further assure the participant is safe to take more drug.
Maybe there are other good methods, but my point is a good strategy should be demanded to protect participants’ safety not just by signing a paper.