I do not have any experience with clinical trials, but I think you raise a very important issue. Does over-regulation lead to a decrease in innovation? I believe that it definitely does, and there is a very delicate balance between sufficient regulation to ensure products released to the market are safe and too much regulation that prevents products with high potential clinical benefit from ever reaching the market because of all the regulatory hurdles. I think that in the future there will be an effort to streamline the regulatory path, because it has reached a point where it had become very burdensome to get a product to market.