The biggest advantage to in hiring CRO is the expertise and experience that the company would provide. Do to their sole role in the industry. And the second biggest would be its cost efficiency of hiring an outside company to do the heavy lifting. Their developed system would Speedline the process turns of getting the maximum value from the money spent. The disadvantages could be actually hiring a trusted company that will be able to provide the necessary service. A second could be IP and confidentiality management, there would be a need for a strong legal team. And lastly, issue of communication management.