The first challenge that comes to mind would be the FDA guidelines. But other challenges could be that each project has different specifications. Project managers for medical devices have to make sure the device works for every type of person that could be using that device. They have to make sure it is adjustable to every body type whereas a project manager for a building does not have to worry about it. Also a project manager for medical devices has to make sure the project that is being started is not a project that has been done already. Also when it comes to medical devices the project manager has to make sure it can actually be made and that it is practical. When making buildings that is not really a problem because there will always be a way to make a building.