Placebo controlled trials are ethical if the individual who is not receiving the correct treatment, is not in serious danger regarding their health. They are also ethical because all individuals have to sign an informed consent form beforehand, agreeing that they know about the chance of a placebo, but that the medicine may have significant advantages if they receive the treatment. Placebo trials are necessary because they allow the doctors or the sponsors to see the real effects of the drug. If an individual is taking a drug that is supposed to cure depression, they may immediately start to feel better after taking the drug, because that is what the results and effects are supposed to be. The drug may not cure depression but the patients mind may trick it self into believing it has been cured and cause a change in emotions. The placebo will allow the doctors to see if the drug is actually working by noting that people who received the placebo are not feeling any effects at all or if the effects they are feeling are not brought about because of the drug. The disadvantage of using a PCT is that certain patients will not receive the treatment they need. Another disadvantage is that if the doctors do not know who actually received the placebo in a double blind experiment then they may not be able to give the proper assistance to their patients. If a patient is coming to the doctor with a problem that could have been caused by the medication, then the doctor will may not know how to assist until after the trial is over.