I think this law is huge step forward on the clinical world. I can only imagine the difficulty that comes with finding willing participants for certain experiments. Dr. Simon mentioned some college buddies who would try these new drugs in order to make a quick buck, but perhaps did not realize the risk they put themselves in the process. For most, a monetary reward is the only thing enticing them to agree to the trials, as they may be in a desperate point in their lives and willing to do anything. For some trials though, financial compensation may not be enough for anyone. I know in the past before the FDA was really established and informed consent was law, doctors would perform experiments on any patients they could take advantage of such as people with mental illness, mental handicaps, or the homeless. This way if anything went wrong they may be able to avoid any consequences. The Right To Try law gives even the most risky drugs and devices a chance at making a medical breakthrough. I know if I was terminally ill and there was no progress after exhausting all approved options, I would be willing to try anything if it was a chance at a few more months or improved bodily function. Unfortunately some advances cannot be achieved without some casualties, but in sacrificing a few, many can be saved and this is one way to accomplish that legally and ethically.