It is hard to say if it is ethical or not when I thought about these questions. One side of it that these been tried on animals before the clinical trials so we sort of know how it works but not fully especially on the human body and how it will react. I Think people agree to go through these trial because they are suffering from a disease and they hope to find a medical treatment along the way with the doctoral studies. Also, unless the doctor is clear and explain the pros and cons in details and educate the patient on everything, Then it is the patient well to choose either to participate or not. So at this point, I think it is ethical. However, I believe that from a business perspective, sometime everything goes around how to generate money and at this point, it is in the gray area if whether it is ethical or not. One example came to my mind that it is like soldiers in the army, they sacrifice their lives to save our nation and families with there own well.