Risk/Benefit ratio sometimes leads to gain more profit and sometimes may leads to loss for the medical device. Most of the companies in other sector takes risk in order to upgrade product, While in the medical field I have noticed that device takes a lot of time for the upgrade maybe the company want to stick same protocol, don't want to take risk as it is related to patient's health

The Risk/Benefit Ratio is a way of comparing the risks of an action to the benefits that will come if that action is taken. If the benefits are relatively high compared to the risks, then it's mostly worth taking the action because the benefits will outweigh the potential negative consequences that may arise. Also, it gives an indication if it's safe to take the risk because if there are more benefits than risks, then odds are that it will yield good results because positive results are more likely to be achieved than negative results because there are more of them that are expected. One way to optimize this ratio is to try to understand and critically think about the action so that all possible consequences could be recorded. It's important to not miss anything important about the action so that the Risk/Benefit Ratio for the task becomes more valid. Researching and brainstorming every aspect of the task may not optimize the ratio, but it will give a better or more valid ratio, one that is closer to the true ratio for the action. This is the major way of optimizing the ratio as knowing is half the battle. If it turns out the risk/benefit ration is actually high, then it will tell you to focus on other actions that may be taken to move forward.

While a risk to benefit ratio may be used to determine the approval or continuation of a project, the magnitude of results certainly depends on the risks associated with the project. The risk to benefit analysis may tolerate a higher ratio when dealing with risks that don’t necessarily pose a significant issue for the end user, whereas the analysis may tolerate a lower ratio if this risk poses significant issues. All in all, human justification and reasoning is necessary when performing risk to benefit analysis.