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  • ajm73 replied to the topic Double Blind Vs Single blind Study in the forum Clinical Research Basics 6 years, 5 months ago

    Overall, double-blind studies are not meant to increase some sort of significance to the investigator, but is more about collecting good data that is not tainted. In single blind studies, there is chance of bias occluding results, therefore causing data to not be reflective of reality. In a double blind study however, the element of bias is eliminated as even the investigators are not aware of who get’s what. In these cases, a third party is brought on in order to facilitate the distribution of drugs. This third party does not allow either of the two groups to know what is what, so as to eliminate the bias. Of course, all of this depends on whether or not this third party organization is also unbiased, but that is something that must be taken as a given. Overall, when a double blind study is done, the data can be seen as more valid and trustworthy when compared to data from a single blind study, for reasons mentioned above.