When one is at the pre-clinical step of their research project, there are many crucial and resource-driven factors that will come against the flawless plan laid out. In cases where the research facility is 1000 miles away, these factors seem even more risky. Time, money, people, modes of transportation, ordering animals, getting the right type/species of animals, the environment, etc. Everything plays a roll in how the tests go. Even if all resources are met, there is more to what determines a test, the procedures/protocols followed, culture, permits and trainings can also vary from location to location. Making sure all of these factors and more are no hindrance are the great challenges that must be sorted out before even beginning animal testing when going to a location that is 1000 miles away.