The CRA is responsible for initiation ,conduct of clinical trials and ensuring that scientific data have been collected and protecting the right and safety of patients. CRA should have a medical background because they are familiar working with patient health chart and clinical health records and they understand data collected during studies General educational qualification for CRA is typically a medical background ,However people having skills like leadership, negotiation, presentation skills, administrative skills and knowledge of GCP can also be CRA. Ability to travel also play key role CRA’s expected to travel to various research sites and have ability to handle domestic as well as international sites is key skill for CRA role. In order to expand knowledge without medical background to meet the specific requirement there are several trainings.