I think placebo controlled trial are very important because this would help subject have control Vs experimental subject which would help better understand the trials which would help develop the treatment in an effective way. Because one should always have something to compare the results. I also agree that in certain cases Placibo itself would cure the disease and than we would have two ways to cure to cure. In cases double blind might help but I think if only patients blind and Investigator knows what they administer would be really benificial for treatment like this.