I think with every new procedure being introduce or proposed it always has its adv and disadvantage, but i think in case of medicine something which has proven itself in clinical trial show how safe the procedure is, Even in cases when any adverse effects or any risk are shown setps can be taken to avoid those duringfg treatment. But from what I believe Something is invented when people think either its not available or the current treatment is too risky with very less successful outcomes.
Advantages:
You may have access to new treatments that work.
There may be fewer side effects compared to the standard treatment.
You may have more regular tests, which some people find reassuring.
You may help to improve future cancer treatments and medical knowledge.

Possible disadvantages
The new treatment may not be any better than your current treatment.
There is a risk that the new treatment may not work for you.
There may be more side effects compared to the standard treatment.
The trial may not be available at a location that is convenient to you.
You may have to go to hospital more often for tests and treatment, which can be inconvenient.
You may not like the uncertainty of not knowing whether you are taking an active new drug, the standard treatment, or a placebo.

With all said most disadvantages are to the patients who participate to be in the trial since the procedure has never been used on humans before but with this said they sign the consent form only when they believe that this there short worth trying or with they believe that it gonna work. So I think no one as certain are facing all advantages or disadvantage.